Manufacturers

Cipla Ltd

Salt Composition

Calcitonin (Salmon) (200IU)

Medicine Type

drugs

Introduction

In Post menopausal osteoporosis Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Calcinase Nasal Spray slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. Use it as advised by the doctor and follow your doctor’s instructions carefully.

Benefits

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Description

Calcinase Nasal Spray is a medicine used for the treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures. It may also be used for bone pain associated with Paget's disease.Calcinase Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

How To Use

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Safety Advise

- Alcohol : None

No interaction found/established | - Pregnancy : CONSULT YOUR DOCTOR

Calcinase Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : CONSULT YOUR DOCTOR

Calcinase Nasal Spray is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. | - Driving : None

No interaction found/established | - Kidney : None

No interaction found/established | - Liver : None

No interaction found/established

If Miss

If you miss a dose of Calcinase Nasal Spray, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Packaging Detail

packet of 3.7 ml Nasal Spray

Package

Packet

Qty

3.7 ml

Product Form

Nasal Spray

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Hormones|Habit Forming :: No|Therapeutic Class :: PAIN ANALGESICS

Primary Use

Post menopausal osteoporosis|Paget's disease

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

Use Of

Post menopausal osteoporosis|Paget's disease

Common Side Effect

Runny nose | Nosebleeds | Nasal irritation | Back pain | Joint pain | Headache

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

CONSULT YOUR DOCTOR

Manufacturer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Q A

Q. Does Calcinase Nasal Spray need to be refrigerated?::: Yes, an unopened bottle of Calcinase Nasal Spray need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Calcinase Nasal Spray, store it at room temperature between 15°C and 30°C. | Q. Does Calcinase Nasal Spray increase bone density?::: Calcinase Nasal Spray contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Calcinase Nasal Spray decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.| Q. Can Calcinase Nasal Spray reduce the calcium levels in blood?::: Yes, Calcinase Nasal Spray can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.| Q. How should I use Calcinase Nasal Spray?::: Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days. | Q. Is it fine to use Calcinase Nasal Spray in pregnant women?::: Generally, Calcinase Nasal Spray is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Calcinase Nasal Spray causing birth defects or miscarriage in pregnant women. Calcinase Nasal Spray should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.

How It Works

Calcinase Nasal Spray is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.

Marketer Details

Cipla Ltd | Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Reference

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766. | Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294. | Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85. | Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020313s033lbl.pdf | Calcitonin-salmon [Prescribing Information]. Stein, Switzerland: Novartis Pharma Stein AG; 2017. [Accessed 28 Mar. 2023] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020313s036lbl.pdf