Product Name

Onditron 2mg/5ml Syrup

Manufacturers

Wockhardt Ltd

Salt Composition

Ondansetron (2mg/5ml)

Medicine Type

drugs

Introduction

In Treatment of Nausea Onditron 2mg/5ml Syrup blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Benefits

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Onditron 2mg/5ml Syrup may be taken with or without food, but it is better to take it at a fixed time.

Description

Onditron 2mg/5ml Syrup is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.Onditron 2mg/5ml Syrup may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.Onditron 2mg/5ml Syrup may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Onditron 2mg/5ml Syrup may be taken with or without food, but it is better to take it at a fixed time.

Safety Advise

- Kidney : SAFE IF PRESCRIBED

Onditron 2mg/5ml Syrup is safe to use in patients with kidney disease. No dose adjustment of Onditron 2mg/5ml Syrup is recommended. | - Liver : CAUTION

Onditron 2mg/5ml Syrup should be used with caution in patients with liver disease. Dose adjustment of Onditron 2mg/5ml Syrup may be needed. Please consult your doctor.In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.

Kidneyinteraction

SAFE IF PRESCRIBED

Liverinteraction

CAUTION

Manufacturer Address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India

Q A

Q. What is Onditron 2mg/5ml Syrup used for?::: Onditron 2mg/5ml Syrup is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Onditron 2mg/5ml Syrup to your child to prevent vomiting post-procedure. Apart from this, Onditron 2mg/5ml Syrup is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Onditron 2mg/5ml Syrup to your child for a few days. Stick to the dose for best results.| Q. What if my child takes too much Onditron 2mg/5ml Syrup?::: Onditron 2mg/5ml Syrup is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Onditron 2mg/5ml Syrup can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.| Q. How should Onditron 2mg/5ml Syrup be stored?::: Onditron 2mg/5ml Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.| Q. Can other medicines be given at the same time as Onditron 2mg/5ml Syrup?::: Onditron 2mg/5ml Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Onditron 2mg/5ml Syrup. Also, check with your child’s doctor before giving any medicine to your child.| Q. In what conditions do I need to call my child’s doctor right away?::: Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.| Q. My child is having a migraine and is on medication. Can I give Onditron 2mg/5ml Syrup along with it?::: Avoid combining Onditron 2mg/5ml Syrup with such medicines because concomitant use of Onditron 2mg/5ml Syrup with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

How It Works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Onditron 2mg/5ml Syrup just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Interaction

Onditron 2mg/5ml Syrup & Montokuf 15mg Syrup :

Ondansetron may reduce the effect of Codeine. | Onditron 2mg/5ml Syrup & Acicod 10mg Tablet :

Ondansetron may reduce the effect of Codeine. | Onditron 2mg/5ml Syrup & Montokuf Plus 15mg Syrup :

Ondansetron may reduce the effect of Codeine. | Onditron 2mg/5ml Syrup & Markodin Syrup :

Ondansetron may reduce the effect of Codeine. | Onditron 2mg/5ml Syrup & Lincotuss 15mg Syrup :

Ondansetron may reduce the effect of Codeine. | Onditron 2mg/5ml Syrup & PARVODEX 65MG CAPSULE :

Ondansetron may reduce the effect of Dextropropoxyphene. | Onditron 2mg/5ml Syrup & Nalfy 10mg Injection :

Ondansetron may reduce the effect of Nalbuphine. | Onditron 2mg/5ml Syrup & Nacphin Injection :

Ondansetron may reduce the effect of Nalbuphine. | Onditron 2mg/5ml Syrup & Intapan Kit Injection :

Ondansetron may reduce the effect of Nalbuphine. | Onditron 2mg/5ml Syrup & Ruffy 20mg Injection :

Ondansetron may reduce the effect of Nalbuphine.

Marketer Details

Wockhardt Ltd | Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India

Reference

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42. | Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285 | Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf | Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from: https://www.childrensmn.org/educationmaterials/childrensmn/article/15755/ondansetron-zofran/ | Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024. [Accessed 25 Jul. 2024] (online) Available from: https://rwandafda.gov.rw/wp-content/uploads/2023/04/Emitino%20-%20Ondansetron%20Oral%20Solution%20USP%202mg%20per%205ml%20-%20SmPC.pdf