Manufacturers

Bharat Serums & Vaccines Ltd

Salt Composition

Hydralazine (20mg)

Medicine Type

drugs

Introduction

In Hypertension (high blood pressure) Dralgeen 20mg Injection is a medicine used to treat severe or life-threatening hypertension (high blood pressure). It increases the flow of blood and oxygen to the heart and other organs by relaxing blood vessels, thereby, lowering your blood pressure. It is usually given as a slow injection by a doctor or healthcare professional.u003cbr>u003cbr>If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. It must be taken regularly as prescribed to be effective.

Benefits

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Description

Dralgeen 20mg Injection belongs to a class of drugs known as vasodilators. It is used for the treatment of severe or life-threatening hypertension (high blood pressure), when the drug cannot be given orally or when there is an urgent need to lower blood pressure in hospitalised patients.Dralgeen 20mg Injection works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily. It is given under the supervision of a healthcare professional and should not be self administered. Certain patients (especially those with marked kidney damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes.Dralgeen 20mg Injection should be used immediately after opening. It should not be added to other solutions. It may discolor upon contact with metal; discolored solutions should be discarded. Some of the common side effects of this medicine are headache, loss of appetite, nausea, vomiting, diarrhea and increased heart rate. Please contact your doctor if these side effects do not resolve or persist for a longer duration.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety Advise

- Alcohol : UNSAFE

It is unsafe to consume alcohol with Dralgeen 20mg Injection. | - Pregnancy : CONSULT YOUR DOCTOR

Dralgeen 20mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : SAFE IF PRESCRIBED

Dralgeen 20mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. | - Driving : UNSAFE

Dralgeen 20mg Injection may cause side effects which could affect your ability to drive.As Dralgeen 20mg Injection may cause headaches or lead to difficulty in concentration and this may affect your ability to drive. | - Kidney : CAUTION

Dralgeen 20mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Dralgeen 20mg Injection may be needed. Please consult your doctor.Regular monitoring of blood pressure is recommended for better dose adjustment. | - Liver : CAUTION

Dralgeen 20mg Injection should be used with caution in patients with liver disease. Dose adjustment of Dralgeen 20mg Injection may be needed. Please consult your doctor.

If Miss

If you miss a dose of Dralgeen 20mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

Packaging Detail

vial of 1 Injection

Package

Vial

Qty

1

Product Form

Injection

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Phthalazines Derivatives|Habit Forming :: No|Therapeutic Class :: CARDIAC|Action Class :: Potassium channel opener

Primary Use

Hypertension (high blood pressure)

Storage

Store below 30°C

Use Of

Hypertension (high blood pressure)

Common Side Effect

Diarrhea | Headache | Increased heart rate | Loss of appetite | Nausea | Palpitations | Vomiting

Alcoholinteraction

UNSAFE

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

SAFE IF PRESCRIBED

Drivinginteraction

UNSAFE

Kidneyinteraction

CAUTION

Liverinteraction

CAUTION

Manufacturer Address

17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Q A

Q. What is Dralgeen 20mg Injection? What is it used for?::: Dralgeen 20mg Injection belongs to a class of medicines known as potassium channel openers. It helps in the removal of potassium from the walls of arteries. This results in increased space in the arteries for the blood to flow easily, thereby reducing the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for the treatment of angina.| Q. How long does it take Dralgeen 20mg Injection to start working?::: Dralgeen 20mg Injection starts working after about an hour of taking the medicine. However, full benefits may be seen only after 4 to 5 days. Consult your doctor if you do not notice any significant improvement in your condition.| Q. What if somebody accidentally takes an excess of Dralgeen 20mg Injection?::: Taking Dralgeen 20mg Injection in excess may cause low blood pressure and the person may feel weak or dizzy. Also, one may experience irregular or fast heartbeat. In case of an overdose, immediately consult the doctor and seek emergency medical help.| Q. Can I take Dralgeen 20mg Injection if I am taking aspirin?::: You should avoid taking Dralgeen 20mg Injection and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor if you notice blood in your stool or vomit while using Dralgeen 20mg Injection.| Q. Who should not use Dralgeen 20mg Injection?::: People who are allergic to Dralgeen 20mg Injection or any of its ingredients should avoid using Dralgeen 20mg Injection. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Dralgeen 20mg Injection. Additionally, it is advised to avoid using Dralgeen 20mg Injection in people taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat). This is because these medicines may interfere with the working of Dralgeen 20mg Injection and affect your blood pressure. Fluctuations in blood pressure could also be due to low blood volume.| Q. Can Dralgeen 20mg Injection affect my sex life?::: No, Dralgeen 20mg Injection does not affect your sex life. However, it is not recommended to take Dralgeen 20mg Injection with other medications used for the treatment of erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine). Taking these together can lead to a serious drop in your blood pressure. Consult your doctor if you are not sure.

How It Works

Dralgeen 20mg Injection is a potassium channel opener. It works by relaxing blood vessels which lowers blood pressure and allows more blood and oxygen to reach the heart and other organs.

Interaction

Dralgeen 20mg Injection & Nimulid Syrup :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nised 50mg Syrup :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nise Tablet :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nimegesic Oral 50mg Suspension :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Neemact 100mg Tablet MD :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nimlin MD 100mg Tablet :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nyci 100mg Tablet :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nimax 100mg Tablet :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nimax-MD 100mg Tablet :

Nimesulide may reduce the effect of Hydralazine. | Dralgeen 20mg Injection & Nimcart 100mg Tablet MD :

Nimesulide may reduce the effect of Hydralazine.

Marketer Details

Bharat Serums & Vaccines Ltd | 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Reference

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 779-81. | Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 178-79. | Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 658-59. | Hydralazine Hydrochloride Injection. Shirley, New York: American Regent Inc.; 2013. [Accessed 22 Jan. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/040136s005lbl.pdf | Drugs.com. Hydralazine Pregnancy and Breastfeeding Warnings. [Accessed 18 Mar. 2019] (online) Available from: https://www.drugs.com/pregnancy/hydralazine.html | Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 18 Mar. 2019] (online) Available from: https://www.scielo.br/j/jped/a/pKPFtLMX4jNH6tTtrqNwb4r/?format=pdf&lang=en