Manufacturers

SPM Drugs Pvt Ltd

Salt Composition

Furosemide (10mg)

Medicine Type

drugs

Introduction

In Treatment of Hypertensive emergency Synate 10mg Injection blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heart beat with less force thereby lowering your blood pressure. This medicine is injected into a vein under the supervision of a doctor. It is used for immediate reduction of very high blood pressure (hypertensive emergency). A controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.

Benefits

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Description

Synate 10mg Injection belongs to a group of medicines called diuretics. It is used for the emergency treatment of very high blood pressure (hypertensive emergency), as it reduces the blood pressure immediately. It also rapidly reduces the swelling (edema) caused by too much water in the body.Synate 10mg Injection helps your body get rid of extra water and salt through urine. It is commonly used to treat people with excess fluid build-up due to heart failure, liver or kidney disease. It is injected into a vein under the supervision of a doctor. Your doctor may monitor your blood pressure after giving this medicine.Common side effects of this medicine include dizziness, weakness, dehydration, decreased potassium level in blood, increased blood uric acid, decreased magnesium level in blood, and increased thirst. These are usually mild and disappear after a short time. Consult your doctor if they bother you or do not go away.Before taking this medicine, let your doctor know if you have any liver problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Regular monitoring of kidney function tests and electrolyte levels is important while using this medicine.It may reduce the potassium level in your blood so your doctor may ask you to add potassium-rich foods to your diet (such as bananas, coconut water, etc.) or prescribe supplements. Any medication that is advised by your doctor for the long-term treatment of your underlying condition should be continued even after this emergency injection.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety Advise

- Alcohol : UNSAFE

It is unsafe to consume alcohol with Synate 10mg Injection. | - Pregnancy : CONSULT YOUR DOCTOR

Synate 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : CONSULT YOUR DOCTOR

Synate 10mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. | - Driving : UNSAFE

Synate 10mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. | - Kidney : SAFE IF PRESCRIBED

Synate 10mg Injection is safe to use in patients with kidney disease. No dose adjustment of Synate 10mg Injection is recommended.However, use of Synate 10mg Injection is not recommended in severe kidney disease patients who are unable to pass urine or the kidney damage is due to some medicines. Please inform your doctor. | - Liver : CAUTION

Synate 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Synate 10mg Injection may be needed. Please consult your doctor.

If Miss

If you miss a dose of Synate 10mg Injection, consult your doctor.

Packaging Detail

vial of 2 ml Injection

Package

Vial

Qty

2 ml

Product Form

Injection

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Sulphamoyl derivatives|Habit Forming :: No|Therapeutic Class :: CARDIAC

Primary Use

Treatment of Hypertensive emergency|Treatment of Edema

Storage

Store below 30°C

Use Of

Treatment of Hypertensive emergency|Treatment of Edema

Common Side Effect

Dizziness | Weakness | Dehydration | Decreased potassium level in blood | Increased blood uric acid | Increased thirst | Decreased magnesium level in blood

Alcoholinteraction

UNSAFE

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

CONSULT YOUR DOCTOR

Drivinginteraction

UNSAFE

Kidneyinteraction

SAFE IF PRESCRIBED

Liverinteraction

CAUTION

Manufacturer Address

SF 52/1 Main Road, K.R.Palayam, Bhavani Pincode - 638 301, Tamil Nadu, India.

Q A

Q. How is Synate 10mg Injection different from Torasemide?::: Both Synate 10mg Injection and Torasemide are loop diuretics. They are used to treat high blood pressure and edema caused by an underlying liver, kidney or lung diseases. Unlike Torasemide, Synate 10mg Injection is also used in the treatment of hypercalcemia (high calcium levels in the blood). Torasemide has a longer duration of action and is safer to use in patients with renal failure, as compared to Synate 10mg Injection.| Q. Should you drink a lot of water when taking Synate 10mg Injection?::: It is advised to take an adequate amount of water if you are taking Synate 10mg Injection. This is because Synate 10mg Injection works by eliminating the extra fluid and electrolytes from your body by increasing the urine production. This elimination of fluids may increase the chances of dehydration if you sweat a lot, exercise vigorously or if the climate is hot. However, if you have kidney or heart problems, you must consult your doctor who will suggest the amount of water that you should be taking. Consult your doctor for any further query or concern.| Q. What is Synate 10mg Injection used for?::: Synate 10mg Injection is used in emergency conditions to lower very high blood pressure (hypertensive crisis). It effectively lowers and normalizes blood pressure rapidly, thus preventing heart attack or stroke. It also helps to remove excess fluids and electrolytes from the body and reduces swelling (edema) due to fluid retention.| Q. What are the side effects of Synate 10mg Injection?::: The most common side effects of Synate 10mg Injection are dizziness, weakness, dehydration, decreased potassium and magnesium levels in blood and increased thirst. You may also notice some injection site reactions such as swelling, pain and redness. However, these are temporary and usually resolve on their own. Consult your doctor if the symptoms persist for long or worry you.| Q. How long does a Synate 10mg Injection last?::: A. Synate 10mg Injection starts acting as early as five minutes and its effect lasts for about two hours. Synate 10mg Injection may cause depletion of sodium, chloride, water and other minerals from the body. Therefore, close monitoring is required if a person is being treated with Synate 10mg Injection.| Q. What other lifestyle changes should I make while taking Synate 10mg Injection?::: Lifestyle changes play a major role in keeping you healthy. Stop smoking and taking alcohol as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Avoid taking excess salt in your diet. Practice yoga or meditation and find ways to reduce or manage stress in your life. Ensure that you have a sound sleep every night as this also reduces your stress and hence helps in keeping your blood pressure normal. Consult your doctor if you need any further help to get maximum benefit of Synate 10mg Injection and to keep healthy.| Q. Can Synate 10mg Injection cause weight gain?::: No, Synate 10mg Injection does not cause weight gain. On the contrary, you may lose weight as it makes your body get rid of the excess of fluids from your body.

How It Works

Synate 10mg Injection is a diuretic. It removes extra water and certain electrolytes from the body by increasing the amount of urine produced.

Interaction

Synate 10mg Injection & Cotaspirin 50mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Cotaspirin 500mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Amboxy Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Aspirin 300mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Loprin-DS Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Gra 165mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Aspin 300mg Tablet DT :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Sprintas 75mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Actisprin 150mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity. | Synate 10mg Injection & Actisprin 75mg Tablet :

Aspirin reduces the effect of Furosemide and may increase the risk of renal damage, ear damge and toxicity.

Marketer Details

SPM Drugs Pvt Ltd | SF 52/1 Main Road, K.R.Palayam, Bhavani Pincode - 638 301, Tamil Nadu, India.

Reference

Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 682-84. | Opie LH, Victor RG, Kaplan NM. Diuretics. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 95-97. | Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 600-601. | Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Fosinopril. [Updated 2019 Feb 28]. [Accessed 19 Feb. 2020] (online) Available from: https://www.ncbi.nlm.nih.gov/books/NBK500799/ | Furosemide [Drug Label]. Morton Grove, IL: Morton Grove Pharmaceuticals, Inc.; 2019. [Accessed 25 Jul. 2024] (online) Available from: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=30cd95a8-ee0d-413d-b26a-6f042e8e1892&type=display