Manufacturers

Novartis India Ltd

Salt Composition

Rifampicin (600mg) + Isoniazid (300mg)

Medicine Type

drugs

Introduction

In Treatment of Tuberculosis (TB) Rimactazid Plus 600 mg/300 mg Tablet is a combination of medicines that is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Benefits

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rimactazid Plus 600 mg/300 mg Tablet is to be taken empty stomach. u003cbr>Avoid Rimactazid Plus 600 mg/300 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Description

Rimactazid Plus 600 mg/300 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.Rimactazid Plus 600 mg/300 mg Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rimactazid Plus 600 mg/300 mg Tablet is to be taken empty stomach. u003cbr>Avoid Rimactazid Plus 600 mg/300 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety Advise

- Alcohol : UNSAFE

Consuming alcohol while taking Rimactazid Plus 600 mg/300 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction). | - Pregnancy : CONSULT YOUR DOCTOR

Rimactazid Plus 600 mg/300 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : SAFE IF PRESCRIBED

Rimactazid Plus 600 mg/300 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. | - Driving : UNSAFE

Rimactazid Plus 600 mg/300 mg Tablet may cause side effects which could affect your ability to drive.Rimactazid Plus 600 mg/300 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability. | - Kidney : CAUTION

Rimactazid Plus 600 mg/300 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Rimactazid Plus 600 mg/300 mg Tablet may be needed. Please consult your doctor. | - Liver : CAUTION

Rimactazid Plus 600 mg/300 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Rimactazid Plus 600 mg/300 mg Tablet may be needed. Please consult your doctor.Use of Rimactazid Plus 600 mg/300 mg Tablet is not recommended in patients with severe liver disease.

If Miss

If you miss a dose of Rimactazid Plus 600 mg/300 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Packaging Detail

strip of 4 tablets

Package

Strip

Qty

4

Product Form

Tablet

Prescription Required

Prescription Required

Fact Box

Habit Forming :: No|Therapeutic Class :: ANTI INFECTIVES

Primary Use

Treatment of Tuberculosis (TB)

Storage

Store below 30°C

Use Of

Treatment of Tuberculosis (TB)

Common Side Effect

Dark colored urine | Rash | Vomiting | Jaundice | Fever | Increased liver enzymes | Nausea | Peripheral neuropathy (tingling and numbness of feet and hand)

Alcoholinteraction

UNSAFE

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

SAFE IF PRESCRIBED

Drivinginteraction

UNSAFE

Kidneyinteraction

CAUTION

Liverinteraction

CAUTION

Manufacturer Address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Q A

Q. What is Rimactazid Plus 600 mg/300 mg Tablet?::: Rimactazid Plus 600 mg/300 mg Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.| Q. What is the most important information I should know about the Rimactazid Plus 600 mg/300 mg Tablet?::: Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.| Q. What is the best time to take Rimactazid Plus 600 mg/300 mg Tablet?::: Take Rimactazid Plus 600 mg/300 mg Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.| Q. Does Rimactazid Plus 600 mg/300 mg Tablet cause change in urine color/turn urine orange?::: Yes, Rimactazid Plus 600 mg/300 mg Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.| Q. Does the use of Rimactazid Plus 600 mg/300 mg Tablet make birth control pills ineffective?::: Yes, Rimactazid Plus 600 mg/300 mg Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).| Q. What are the instructions for storage and disposal of Rimactazid Plus 600 mg/300 mg Tablet?::: Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

How It Works

Rimactazid Plus 600 mg/300 mg Tablet is a combination of two antibiotics: Rifampicin and Isoniazid, which treats tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

Marketer Details

Novartis India Ltd | Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Reference

Isoniazid/rifampicin. Guildford Surrey: Aventis Pharma Limited; 1999 [revised 12 Mar. 2019]. [Accessed on 10 Apr. 2019] (online) Available from: https://www.medicines.org.uk/emc/product/6123/smpc | Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from: https://accesspharmacy.mhmedical.com/content.aspx?sectionid=124496249&bookid=1810&jumpsectionID=124496261&Resultclick=2 | Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from: https://www.medicines.org.uk/emc/files/pil.4863.pdf