Manufacturers

Intas Pharmaceuticals Ltd

Salt Composition

Cyclophosphamide (200mg)

Medicine Type

drugs

Introduction

In Cancer Chophos 200mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Chophos 200mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Benefits

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Description

Chophos 200mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.Chophos 200mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety Advise

- Alcohol : UNSAFE

It is unsafe to consume alcohol with Chophos 200mg Injection. | - Pregnancy : CONSULT YOUR DOCTOR

Chophos 200mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. | - Breast feeding : UNSAFE

Chophos 200mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. | - Driving : UNSAFE

Chophos 200mg Injection may cause side effects which could affect your ability to drive.Chophos 200mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive. | - Kidney : CAUTION

Chophos 200mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Chophos 200mg Injection may be needed. Please consult your doctor. | - Liver : CAUTION

Chophos 200mg Injection should be used with caution in patients with liver disease. Dose adjustment of Chophos 200mg Injection may be needed. Please consult your doctor.

Packaging Detail

vial of 1 Injection

Package

Vial

Qty

1

Product Form

Injection

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Nitrogen Mustard Compounds|Habit Forming :: No|Therapeutic Class :: ANTI NEOPLASTICS|Action Class :: Alkylating agent

Primary Use

Cancer|Nephrotic syndrome

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

Use Of

Cancer|Nephrotic syndrome

Common Side Effect

Vomiting | Nausea | Hair loss | Fever | Blood in urine | Diarrhea | Decreased white blood cell count (neutrophils)

Alcoholinteraction

UNSAFE

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

UNSAFE

Drivinginteraction

UNSAFE

Kidneyinteraction

CAUTION

Liverinteraction

CAUTION

Manufacturer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Q A

Q. Can Chophos 200mg Injection cause infertility?::: Yes, Chophos 200mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Chophos 200mg Injection. | Q. Do I need to avoid sun exposure during treatment with Chophos 200mg Injection?::: No, there is no evidence that you need to avoid sun exposure while on Chophos 200mg Injection. Skin and nail discoloration are reported rarely with Chophos 200mg Injection.| Q. Can Chophos 200mg Injection cause cancer?::: Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Chophos 200mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Chophos 200mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.| Q. Is Chophos 200mg Injection chemotherapy medicine?::: Yes, Chophos 200mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.| Q. Can Chophos 200mg Injection be used for non-cancer condition?::: Yes, Chophos 200mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Chophos 200mg Injection for nephrotic syndrome has not been established.| Q. Can Chophos 200mg Injection causes weight loss?::: Yes, Chophos 200mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

How It Works

Chophos 200mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

Interaction

Chophos 200mg Injection & Candid Mouth Paint :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Clospray Mouth Paint :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Cloral Lozenges :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Glenmark Clotrimazole 6 Vaginal Tablet :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Glenmark Clotrimazole 1 Vaginal Tablet :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Dermacan 2% Gel :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Clotrin Mouth Paint :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Gynostatum 2% Vaginal Cream :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Mycocid 100mg Tablet VT :

Clotrimazole may increase the blood level of Cyclophosphamide. | Chophos 200mg Injection & Mycocid Mouth Wash :

Clotrimazole may increase the blood level of Cyclophosphamide.

Marketer Details

Intas Pharmaceuticals Ltd | Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Reference

Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975. | Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38. | Cyclophosphamide monohydrate. Camberley, Surrey: Sandoz Limited; 2014 [revised 07 Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from: https://www.medicines.org.uk/emc/medicine/29592 | Cyclophosphamide. Baxter Health Corporation; 1959. [Accessed 26 Mar. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/040745Orig1s003lbl.pdf | Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from: https://www.scielo.br/j/jped/a/pKPFtLMX4jNH6tTtrqNwb4r/?format=pdf&lang=en