Manufacturers

Intas Pharmaceuticals Ltd

Salt Composition

Teriparatide (750mcg)

Medicine Type

drugs

Introduction

In Osteoporosis Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. Osteofrac 750mcg Injection helps treat osteoporosis in men as well as in women after menopause. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered. You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Benefits

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Description

Osteofrac 750mcg Injection is a man-made version of parathyroid hormone used to treat men and postmenopausal women who have severe osteoporosis with a high risk of fractures. It works by stimulating new bone formation, which improves bone density and decreases the risk of spinal fractures.Osteofrac 750mcg Injection should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better. It should be stored in the refrigerator at a temperature of  2°C to 8°C.Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness) and leg cramps. consult with your doctor if any of these bother you or do not go away. Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety Advise

- Alcohol : CAUTION

Caution is advised when consuming alcohol with Osteofrac 750mcg Injection. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR

Osteofrac 750mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : CONSULT YOUR DOCTOR

Information regarding the use of Osteofrac 750mcg Injection during breastfeeding is not available. Please consult your doctor. | - Driving : UNSAFE

Osteofrac 750mcg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. | - Kidney : CAUTION

Osteofrac 750mcg Injection should be used with caution in patients with kidney disease. Dose adjustment of Osteofrac 750mcg Injection may be needed. Please consult your doctor.Use of Osteofrac 750mcg Injection is not recommended in patients with severe kidney disease. | - Liver : CONSULT YOUR DOCTOR

There is limited information available on the use of Osteofrac 750mcg Injection in patients with liver disease. Please consult your doctor.

If Miss

If you miss a dose of Osteofrac 750mcg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Packaging Detail

vial of 3 ml Injection

Package

Vial

Qty

3 ml

Product Form

Injection

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Parathyroid Hormone Analogs|Habit Forming :: No|Therapeutic Class :: HORMONES

Primary Use

Osteoporosis

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

Use Of

Osteoporosis

Common Side Effect

Joint pain | Injection site reactions (pain, swelling, redness) | Nausea | Leg cramps

Alcoholinteraction

CAUTION

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

CONSULT YOUR DOCTOR

Drivinginteraction

UNSAFE

Kidneyinteraction

CAUTION

Liverinteraction

CONSULT YOUR DOCTOR

Manufacturer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Q A

Q. Is Osteofrac 750mcg Injection a steroid?::: No, Osteofrac 750mcg Injection is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of postmenopausal age group and in men who have increased risk of fracture.| Q. Can I take this medication in long term for osteoporosis?::: Osteofrac 750mcg Injection should not be taken for longer than 2-year course. It is important to inform the doctor if you have taken this medication in the past, as you should not receive more than one treatment of 24 months course more than once in your lifetime. | Q. How is Osteofrac 750mcg Injection stored at home?::: Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious, the temperature should not decrease further as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Osteofrac 750mcg Injection pens close to the ice compartment of the refrigerator. If properly stored this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days please discard it safely.| Q. Who should not use Osteofrac 750mcg Injection?::: The doctor will decide whether the medicine is required for a patient or not. There are few conditions in which the use of Osteofrac 750mcg Injection should be avoided such as in patients with kidney impairment, Paget’s disease, any type of bone cancers or unexplained high levels of serum calcium. It should also be avoided by children, young adult or growing age, pregnant or lactating females. Hence, before starting the medication inform the doctor about any medical condition and the medication you are taking. This will help the doctor to design a proper therapy for you.

How It Works

Osteofrac 750mcg Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.

Marketer Details

Intas Pharmaceuticals Ltd | Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Reference

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766. | Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300 | Teriparatide. Indianapolis, Indiana: Lilly France; 2008. [Accessed 02 Apr. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021318s015lbl.pdf | Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from: https://cdscoonline.gov.in/CDSCO/Drugs | Teriparatide injection [Prescribing Inforamtion]. Indianapolis, IN: : Lilly USA, LLC; 2021. [Accessed 20 Feb. 2024] (online) Available from: https://pi.lilly.com/us/forteo-pi.pdf