Manufacturers

Lupin Ltd

Salt Composition

Pioglitazone (15mg)

Medicine Type

drugs

Introduction

In Treatment of Type 2 diabetes mellitus Path 15 Tablet improves the body’s response to the hormone insulin responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.u003cbr>Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Benefits

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Path 15 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Description

Path 15 Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.Path 15 Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.The most common side effects of taking this medicine include headache, sinusitis, muscle pain, and pharyngitis. Consult your doctor if any of these side effects bother you or persist for a longer duration.You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Path 15 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety Advise

- Alcohol : UNSAFE

It is unsafe to consume alcohol with Path 15 Tablet. | - Pregnancy : CONSULT YOUR DOCTOR

Path 15 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : CAUTION

Path 15 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.Monitor the breastfed baby’s blood sugar during treatment with Path 15 Tablet | - Driving : SAFE

Path 15 Tablet does not usually affect your ability to drive. | - Kidney : SAFE IF PRESCRIBED

Path 15 Tablet is safe to use in patients with kidney disease. No dose adjustment of Path 15 Tablet is recommended. | - Liver : CAUTION

Path 15 Tablet should be used with caution in patients with liver disease. Dose adjustment of Path 15 Tablet may be needed. Please consult your doctor.Use of Path 15 Tablet is not recommended in patients with severe liver disease.

If Miss

If you miss a dose of Path 15 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Packaging Detail

strip of 15 tablets

Package

Strip

Qty

15

Product Form

Tablet

Prescription Required

Prescription Required

Fact Box

Chemical Class :: Thiazolidinedione Derivative|Habit Forming :: No|Therapeutic Class :: ANTI DIABETIC|Action Class :: Thiazolidinedione(PPAR gamma agonist)

Primary Use

Treatment of Type 2 diabetes mellitus

Storage

Store below 30°C

Use Of

Treatment of Type 2 diabetes mellitus

Common Side Effect

Headache | Sore throat | Sinus inflammation | Muscle pain

Alcoholinteraction

UNSAFE

Pregnancyinteraction

CONSULT YOUR DOCTOR

Lactationinteraction

CAUTION

Drivinginteraction

SAFE

Kidneyinteraction

SAFE IF PRESCRIBED

Liverinteraction

CAUTION

Manufacturer Address

3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Q A

Q. Can Path 15 Tablet cause weight gain?::: Path 15 Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.| Q. Can Path 15 Tablet cause heart failure?::: Path 15 Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Path 15 Tablet is used with insulin.| Q. Can you take Path 15 Tablet and metformin together?::: Yes, Path 15 Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.| Q. What time of day should you take Path 15 Tablet?::: It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Path 15 Tablet exactly as prescribed by your doctor.| Q. How long do I need to take Path 15 Tablet? Can I stop the medicine for some time?::: Continue taking Path 15 Tablet as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.| Q. Does Path 15 Tablet affect liver?::: Yes, Path 15 Tablet may cause an increase in liver enzymes, and treatment with Path 15 Tablet should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Path 15 Tablet should not be prescribed to patients with liver disease.| Q. What kind of medicine is Path 15 Tablet? Is it like metformin?::: Path 15 Tablet belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.| Q. Can Path 15 Tablet cause bladder cancer?::: Path 15 Tablet may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Path 15 Tablet should not be used in patients with a prior history of bladder cancer or having bladder cancer.

How It Works

Path 15 Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Interaction

Path 15 Tablet & Keno 200mg Tablet :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Tmp 300mg Tablet :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Tabrol Syrup :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Metstol 100mg Tablet :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Bacstol Tablet :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Omstat Tablet 10mg :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Bacstol 200 Tablet :

Use of Pioglitazone and Trimethoprim should be avoided at the same time. | Path 15 Tablet & Amiur 5mg Tablet :

There is no significant interaction. But if higher doses of Amiloride are used along with Pioglitazone, it is recommended to monitor the blood glucose levels regularly. | Path 15 Tablet & Betasone 4mg Injection :

It is recommended to monitor the blood glucose level regularly as cases of high blood sugar levels have been seen in some patients. | Path 15 Tablet & Decdan B 4mg/ml Injection :

It is recommended to monitor the blood glucose level regularly as cases of high blood sugar levels have been seen in some patients.

Marketer Details

Lupin Ltd | 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Reference

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61. | Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 742-43. | Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1124-25. | Pioglitazone. Deerfield, Illinois; Takeda Pharmaceuticals America, Inc.; 1999 [revised Nov. 2013]. [Accessed 28 Jan. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021073s046lbl.pdf | Pioglitazone hydrochloride [Product monograph]. Ontario, Canada: Takeda Canada Inc.; 2018. [Accessed 8 Oct. 2021] (online) Available from: https://www.takeda.com/4ab371/siteassets/en-ca/home/what-we-do/our-medicines/product-monographs/actos/actos-pm-18jan2018-clean_en.pdf | Actos [Summary of Product Characteristics]. County Wicklow, Ireland: Takeda Ireland Limited; 2010. [Accessed 8 October. 2021] (online) Available from: https://www.ema.europa.eu/en/documents/product-information/actos-epar-product-information_en.pdf | Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from: https://www.torrentian.com/pisheet/Upload/PI_Sheet/1781.pdf | Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh, India: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=482cef76-0623-4b4f-a0ea-f008c97b2281&type=display#